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Ketamine Therapy in San Luis Obispo, California

Compare 7 Ketamine Therapy clinics in San Luis Obispo, California that offer care for treatment-resistant depression, anxiety, and PTSD. Review services, ratings, and contact details to find the right provider near you.
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Clinics

7 clinics shown

  • County of San Luis Obispo- Behavioral Health Department

    The County of San Luis Obispo Behavioral Health Department operates a public mental health clinic on Johnson Avenue, providing psychiatric services to county residents who meet eligibility criteria based on diagnosis severity and financial need. The department functions as part of the county government health system, offering medication management, case coordination, and crisis intervention for adults with serious mental illness. Specific treatment modalities such as TMS or ketamine therapy are not listed in available public information; patients should contact the department directly to confirm available services and eligibility requirements.

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  • Innerbloom Ketamine Therapy

    Innerbloom Ketamine Therapy operates a downtown San Luis Obispo clinic on Monterey Street offering Spravato (esketamine nasal spray), IV ketamine, and IM ketamine treatments. The practice provides ketamine-assisted psychotherapy alongside medication administration, incorporating preparation and integration sessions into treatment protocols. Patients are seen for depression, chronic pain, PTSD, anxiety disorders, and substance use conditions. The clinic schedules initial consultations by phone or through its website.

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  • Pacific Psychiatry, Inc.

    Psychiatric evaluations and medication management are provided at Pacific Psychiatry, Inc., an outpatient practice on Ella Street in San Luis Obispo. The clinic serves adults requiring psychiatric care, though specific treatment modalities beyond standard psychiatric services are not detailed in available information. Patients seeking specialized interventions such as TMS or ketamine therapy should contact the practice directly to confirm availability of those treatments.

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  • Peaceful Mind, Inc./A. Anthony Aichouri, MD, PhD

    Dr. A. Anthony Aichouri operates Peaceful Mind, Inc., a psychiatric practice on South Higuera Street in San Luis Obispo. The practice provides psychiatric evaluations and medication management for adults. Specific treatment modalities beyond standard psychiatric care—such as TMS, esketamine, or ketamine therapy—are not detailed in available information; prospective patients should contact the office to confirm current service offerings and availability.

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  • Psychiatric Health Facility - Crestwood (PHF Inpatient) - San Luis Obispo County

    Psychiatric Health Facility - Crestwood operates as a county-administered inpatient psychiatric unit in San Luis Obispo, providing acute stabilization services for adults experiencing psychiatric crises. The facility, located on Johnson Avenue, is part of San Luis Obispo County's public behavioral health system and serves individuals requiring short-term hospitalization for severe mental health symptoms. Treatment focuses on medication stabilization, crisis intervention, and discharge planning rather than outpatient procedures like TMS or ketamine therapy.

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  • Remis Paul M MD

    Dr. Paul Remis operates a psychiatric practice on Higuera Street in San Luis Obispo, providing outpatient mental health services for adults. The practice focuses on general psychiatry, including diagnostic evaluations and medication management for mood, anxiety, and related psychiatric conditions. Specific procedural treatments such as TMS or ketamine therapy are not indicated in available practice information. Patients seeking specialized interventional treatments should contact the office to confirm current service offerings and availability.

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  • Shannon Easton-Carr, MD

    Dr. Shannon Easton-Carr operates a psychiatric practice on South Higuera Street in San Luis Obispo, providing medication management and evaluations for adults with mental health conditions. The practice focuses on general psychiatry services rather than procedural treatments like TMS or ketamine therapy. Patients seeking specialized interventions for treatment-resistant depression should confirm availability of those modalities directly, as they are not indicated in current practice listings.

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About Ketamine Therapy

Ketamine therapy is the broader category of clinical ketamine use for mental health conditions including treatment-resistant depression, anxiety, PTSD, OCD, and chronic suicidal ideation. Unlike Spravato (which is the FDA-approved esketamine nasal spray), most ketamine therapy is provided off-label using racemic ketamine — typically through IV infusion, intramuscular injection, or sublingual lozenges.

Treatment is administered in a clinical setting with continuous medical supervision. A typical IV protocol involves six infusions over two to three weeks, with each infusion lasting 40 to 60 minutes. Patients are monitored throughout for blood pressure changes, dissociative effects, and emotional response. Many clinics provide a calm, dimly lit room with eye masks and music to support a contemplative experience during dosing.

Ketamine acts on the brain's NMDA receptors and glutamate system, which is fundamentally different from how SSRIs and other traditional antidepressants work. Many patients report significant improvement within hours to days of their first session — among the fastest-acting antidepressant effects in clinical use.

Because most ketamine therapy is off-label, insurance coverage is limited and most patients pay out of pocket. Clinics in our directory range from anesthesiology-led infusion centers to integrated psychiatric practices offering ketamine alongside therapy.