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Spravato (Esketamine) in Palm Springs, California

Compare 2 Spravato (Esketamine) clinics in Palm Springs, California that offer care for treatment-resistant depression and major depressive disorder. Review services, ratings, and contact details to find the right provider near you.
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Clinics

2 clinics shown

  • Dr. Esmaeil Sebti

    Dr. Esmaeil Sebti operates a psychiatric practice on El Cielo Road in Palm Springs, providing outpatient mental health services for adults. The practice focuses on psychiatric evaluation and medication management. Specific procedural treatments such as TMS or esketamine are not indicated in available listings; patients seeking those modalities should inquire directly about current service offerings.

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  • Keerthy Sunder M.D.

    Psychiatry services are provided by Dr. Keerthy Sunder at a Palm Springs practice on Paseo Dorotea. The clinic focuses on psychiatric evaluations and medication management for adults. Specific treatment modalities beyond standard psychiatric care—such as TMS, ketamine, or esketamine—are not detailed in available information; prospective patients should inquire directly about specialized treatment options.

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About Spravato (Esketamine)

Spravato is the brand name for esketamine, an FDA-approved nasal spray for treatment-resistant depression and major depressive disorder with suicidal ideation. It's derived from ketamine and works on the brain's glutamate system — a different mechanism than traditional antidepressants like SSRIs.

Treatment is administered only at REMS-certified clinics under direct medical supervision. Patients self-administer the spray under a clinician's guidance, then remain at the clinic for at least two hours of monitoring after each dose. The induction phase typically involves twice-weekly sessions for four weeks, followed by weekly or biweekly maintenance dosing depending on response.

Many patients report meaningful symptom improvement within the first one to two weeks — substantially faster than the 4 to 8 weeks typical of oral antidepressants. Spravato is taken alongside an oral antidepressant, not as a replacement.

The most common side effects are dissociation, dizziness, sedation, and elevated blood pressure during and shortly after dosing. These typically resolve within the two-hour monitoring window. Patients cannot drive on the day of treatment.

Most commercial insurance and Medicare cover Spravato for treatment-resistant depression with prior authorization. Clinics offering Spravato in our directory hold active REMS certification and are staffed to provide the required in-clinic monitoring period.