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Spravato (Esketamine) in Greenbelt, Maryland

Compare 2 Spravato (Esketamine) clinics in Greenbelt, Maryland that offer care for treatment-resistant depression and major depressive disorder. Review services, ratings, and contact details to find the right provider near you.
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Clinics

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  • Lifespan Behavioral Health Services

    Lifespan Behavioral Health Services operates an outpatient mental health practice in Greenbelt, located on Greenway Center Drive near the Capital Beltway. The clinic provides psychiatric evaluations and therapy services for adults dealing with mood disorders, anxiety, and related conditions. Available treatment modalities beyond standard outpatient care are not specified in public listings; patients should contact the practice directly to confirm whether TMS, ketamine, or esketamine treatments are offered. Most sessions are conducted in-person at the Greenbelt office.

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About Spravato (Esketamine)

Spravato is the brand name for esketamine, an FDA-approved nasal spray for treatment-resistant depression and major depressive disorder with suicidal ideation. It's derived from ketamine and works on the brain's glutamate system — a different mechanism than traditional antidepressants like SSRIs.

Treatment is administered only at REMS-certified clinics under direct medical supervision. Patients self-administer the spray under a clinician's guidance, then remain at the clinic for at least two hours of monitoring after each dose. The induction phase typically involves twice-weekly sessions for four weeks, followed by weekly or biweekly maintenance dosing depending on response.

Many patients report meaningful symptom improvement within the first one to two weeks — substantially faster than the 4 to 8 weeks typical of oral antidepressants. Spravato is taken alongside an oral antidepressant, not as a replacement.

The most common side effects are dissociation, dizziness, sedation, and elevated blood pressure during and shortly after dosing. These typically resolve within the two-hour monitoring window. Patients cannot drive on the day of treatment.

Most commercial insurance and Medicare cover Spravato for treatment-resistant depression with prior authorization. Clinics offering Spravato in our directory hold active REMS certification and are staffed to provide the required in-clinic monitoring period.